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HelpTest ID NBLD0668 Synovasure Microbial Antigen Detection, Periprosthetic, Joint Infection
AKA
Synovasure, PJI
Specimen Type/Requirements
Sterile Container - Synovial Fluid Aspiration (*)
Aspirate joint using standard technique. At time of aspiration, ensure that specimen is not diluted by saline lavage, contrast, blood or other non-synovial fluids.
* Transfer 1.0 mL synovial fluid to a white cap Greiner no additive transport tube (available from Sanford Laboratories Supplies).
*Note: If also ordering NBLD0585 Synovasure Alpha Defensin and CRP, Periprosthetic Joint Infection, the volume required for both tests is 1.5 mL of synovial fluid. Only one tube is needed for the shared specimen.
Monday-Friday: Collect and ship room temperature the same day as aspiration.
Saturday-Sunday: Collect and store refrigerated; Ship on Monday.
Note: For best results, specimens should ship the same day as collected.
Indicate source on specimen and order - Example: Right Hip, Left Knee, etc.
Specimen Volume
| Preferred Volume | 1.0 mL |
|---|---|
| Minimum Volume | 1.0 mL |
Stability/Transport
| Room Temperature | 1 day | Preferred for shipping same day (M-F) |
|---|---|---|
| Refrigerated | 5 days* | Preferred for storage if cannot ship same day |
| Frozen | Not Acceptable |
*Overall specimen stability is 5 days and it can be refrigerated for 3 days over the weekend if needed.
Additional Information
This assay is intended for the early detection of microbial antigen in synovial fluid. It can detect microbial antigen in some samples where an organism is present but was not able to be cultured. This panel identifies Staphylococcus species, Enterococcus species, Candida species and Propionibacterium acnes genera, which make up ~70% of all periprosthetic joint infections.
Methodology
Immunometric multiplexed assay and involves the reaction of the microbial antigen present in the sample with a genera-specific anti-microbial antibody conjugated to beads.
Performing Lab
CD Laboratories
Analytic Time
1 - 3 days
CPT
87449 x 3