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Test ID NBLD0472 Acetylcholinesterase, Amniotic Fluid

Useful For

Diagnosing open neural tube defects and, to a lesser degree, ventral wall defects

Specimen Type

Amniotic Fld


Additional Testing Requirements


If chromosome studies are also requested, see CHRAF / Chromosome Analysis, Amniotic Fluid for specimen requirements. When requested with chromosome analysis, the specimen cannot be frozen.



Necessary Information


1. Gestational age at amniocentesis is required.

2. If not ordering electronically, provide gestational age on Second Trimester Maternal Screening Alpha-Fetoprotein / Quad Screen Patient Information (T595) and send with specimen.



Specimen Required


Container/Tube: Amniotic fluid container

Specimen Volume: 1 mL

Collection Instructions: Specimen must be collected between 14 to 21 weeks gestation; 14 to 18 weeks is preferred.


Reject Due To

Gross hemolysis OK
Gross icterus OK

Specimen Minimum Volume

0.3 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Amniotic Fld Refrigerated (preferred) 365 days
  Frozen  365 days
  Ambient  14 days

Day(s) Performed

Tuesday, Thursday

Report Available

3 to 7 days

Method Name

Polyacrylamide Electrophoresis

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

82013

Reporting Name

Acetylcholinesterase, AF

Reference Values

Negative (reported as negative [normal] or positive [abnormal] for inhibitable acetylcholinesterase)

 

Reference values were established in conjunction with alpha-fetoprotein testing and include only amniotic fluids from pregnancies between 14- and 21-weeks gestation.

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

Secondary ID

9287
Sanford Laboratories - Sioux Falls/Rapid City Additional Information:

SANFORD LABORATORY INTERFACE BUILD INFORMATION

Result Code  Result Code Description 
17786 Acetylcholinesterase, AF
17787 Gestational Age (ACHE)