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Test ID BLOD5035 Streptococcus pneumoniae IgG Antibodies, 23 Serotypes, Serum


Ordering Guidance


This test is the preferred test for patients previously tested for Streptococcus pneumoniae serotypes (as part of follow up testing or part of pre/post vaccine assessment).

 

The preferred test for patients being evaluated for possible immunodeficiency or for assessment of pneumococcal vaccination response (initial evaluation) is PNTOR / Streptococcus pneumoniae IgG Antibodies, Total, with Reflex, Serum

 

The preferred test for patients previously tested for total Streptococcus pneumoniae antibodies (as part of follow up testing or part of pre/post vaccine assessment) is PNTO / Streptococcus pneumoniae IgG Antibodies, Total, Serum



Specimen Required


Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial 

Specimen Volume: 0.5 mL

Collection Instructions: Centrifuge and aliquot serum into plastic vial


Secondary ID

619921

Useful For

Assessing the IgG antibody response to active immunization with nonconjugated, 23-valent pneumococcal vaccines

 

Assessing the IgG antibody response to active immunization with conjugated 13-valent, 15-valent and 20-valent pneumococcal vaccines

 

Determining the ability of an individual to produce an antibody response to polysaccharide antigens, as part of the evaluation for humoral or combined immunodeficiencies

Method Name

Bead-Based Multiplex Immunoassay

Reporting Name

S. pneumoniae IgG Ab,23 serotypes,S

Specimen Type

Serum

Specimen Minimum Volume

0.4 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 21 days
  Frozen  21 days

Reject Due To

Gross hemolysis OK
Gross lipemia OK
Gross icterus OK

Reference Values

Results are reported in mcg/mL

 

Serotype

Normal value

1 (1)

≥1.0

2 (2)

≥1.0

3 (3)

≥1.0

4 (4)

≥1.0

5 (5)

≥1.0

8 (8)

≥1.0

9N (9)

≥1.0

12F (12)

≥1.0

14 (14)

≥1.0

17F (17)

≥1.0

19F (19)

≥1.0

20 (20)

≥1.0

22F (22)

≥1.0

23F (23)

≥1.0

6B (26)

≥1.0

10A (34)

≥1.0

11A (43)

≥1.0

7F (51)

≥1.0

15B (54)

≥1.0

18C (56)

≥1.0

19A (57)

≥1.0

9V (68)

≥1.0

33F (70)

≥1.0

Day(s) Performed

Monday through Friday

Report Available

4 to 6 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

86317 x 23

Forms

If not ordering electronically, complete, print, and send a General Request (T239) with the specimen.

Sanford Laboratories - Sioux Falls/Rapid City Additional Information:

SANFORD LABORATORY INTERFACE BUILD INFORMATION

Result Code  Result Code Description 
17674 Serotype 1 (1)
17675 Serotype 2 (2)
17676 Serotype 3 (3)
17677 Serotype 4 (4)
17678 Serotype 5 (5)
17679 Serotype 8 (8)
17680 Serotype 9N (9)
17681 Serotype 12F (12)
17682 Serotype 14 (14)
17683 Serotype 17F (17)
17684 Serotype 19F (19)
17685 Serotype 20 (20)
17686 Serotype 22F (22)
17687 Serotype 23F (23)
17688 Serotype 6B (26)
17689 Serotype 10A (34)
17690 Serotype 11A (43)
17691 Serotype 7F (51)
17692 Serotype 15B (54)
17693 Serotype 18C (56)
17694 Serotype 19A (57)
17695 Serotype 9V (68)
17696 Serotype 33F (70)
25703 Interpretation