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Mayo Clinic Laboratories

Test ID BLOD0415 Apolipoprotein A1 and B, Serum

Useful For

Assessment of cardiovascular risk

 

Follow-up studies in individuals with basic lipid measures inconsistent with risk factors or clinical presentation

 

Definitive studies of cardiac risk factors in individuals with significant family histories of coronary artery disease or other increased risk factors

Specimen Type

Serum


Specimen Required


Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions: Centrifuge and aliquot 1 mL of serum.


Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 8 days
  Frozen  60 days
  Ambient  24 hours

Reject Due To

Gross hemolysis Reject
Gross lipemia OK
Gross icterus Reject

Day(s) Performed

APOA1: Monday through Sunday

APOLB: Monday through Saturday

Report Available

1 to 3 days

Method Name

Automated Turbidimetric Immunoassay

Reporting Name

Apolipoprotein A1 and B, S

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Secondary ID

607593

CPT Code Information

82172 x 2

Reference Values

Males

Age

Apolipoprotein A (mg/dL)

Apolipoprotein B (mg/dL)

Apolipoprotein B/A1 ratio

<24 months

Not established

Not established

Not established

2-17 years

Low: <115

Borderline low: 115-120

Acceptable: >120

Acceptable: <90

Borderline high: 90-109

High: ≥110

<0.8

>18 years

≥120

Desirable: <90

Above Desirable: 90-99

Borderline high: 100-119

High: 120-139

Very high: ≥140

 

Lower Risk: <0.7

Average Risk: 0.7-0.9

Higher Risk: >0.9

Females

Age

Apolipoprotein A (mg/dL)

Apolipoprotein B (mg/dL)

Apolipoprotein B/A1 ratio

<24 months

Not established

Not established

Not established

2-17 years

Low: <115

Borderline low: 115-120

Acceptable: >120

Acceptable: <90

Borderline high: 90-109

High: ≥110

<0.8

>18 years

≥140

Desirable: <90

Above Desirable: 90-99

Borderline high: 100-119

High: 120-139

Very high: ≥140

 

Lower Risk: <0.6

Average Risk: 0.6-0.8

Higher Risk: >0.8

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

Profile Information

Test ID Reporting Name Available Separately Always Performed
RBAA1 Apolipoprotein B/A1 ratio No Yes
APOA1 Apolipoprotein A1, S Yes Yes
APOLB Apolipoprotein B, S Yes Yes

Forms

If not ordering electronically, complete, print, and send a Cardiovascular Test Request Form (T724) with the specimen.

Sanford Laboratories - Sioux Falls/Rapid City Additional Information:

SANFORD LABORATORY INTERFACE BUILD INFORMATION

 Result Code     Result Code Description   
 420  APO B/A1 RATIO
 421  APOLIPOPROTEIN A1
 423  APOLIPOPROTEIN B