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Test ID BLOD0200 Alkaline Phosphatase, Total and Isoenzymes, Serum

Useful For

Aid in the diagnosis and treatment of liver, bone, intestinal, and parathyroid diseases

 

Determining the tissue source of increased alkaline phosphatase (ALP) activity in serum

 

Differentiating between liver and bone sources of elevated ALP

Specimen Type

Serum


Necessary Information


Patient's age and sex are required.



Specimen Required


Patient Preparation: Fasting (8 hours) required

Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions:

1. Within 2 hours of collection, centrifuge the specimen.

2. For red top tubes, immediately aliquot into a plastic vial.

3. For serum gel tubes, serum may sit on gel refrigerated but must be aliquoted within 7 days.


Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Frozen (preferred) 14 days
  Ambient  7 days
  Refrigerated  7 days

Reject Due To

Gross hemolysis Reject
Gross lipemia OK
Gross icterus Reject

Day(s) Performed

Tuesday through Saturday

Report Available

3 to 5 days

Method Name

ALP: Colorimetric

ALPI: Electrophoresis

Reporting Name

Alkaline Phosphatase, Tot and Iso,S

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Secondary ID

622157

CPT Code Information

84075

84080

Reference Values

ALKALINE PHOSPHATASE

Males

0-14 days: 83-248 U/L

15 days-<1 year: 122-469 U/L

1-<10 years: 142-335 U/L

10-<13 years: 129-417 U/L

13-<15 years: 116-468 U/L

15-<17 years: 82-331 U/L

17-<19 years: 55-149 U/L

≥19 years: 40-129 U/L

Females

0-14 days: 83-248 U/L

15 days-<1 year: 122-469 U/L

1-<10 years: 142-335 U/L

10-<13 years: 129-417 U/L

13-<15 years: 57-254 U/L

15-<17 years: 50-117 U/L

≥17 years: 35-104 U/L

 

ALKALINE PHOSPHATASE ISOENZYMES

Ages:

≤17 years: Refence values have not been established for patients less than 18 years of age.

≥18 years:

Liver %: 30.2-74.7

Liver U/L: 15.8-71.9

Bone %: 23.8-68.3

Bone U/L: 12.0-56.7

Intestine %: ≤22.5

Intestine U/L: ≤12.6

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

Profile Information

Test ID Reporting Name Available Separately Always Performed
ALP Alkaline Phosphatase, S Yes Yes
ALPI Alkaline Phosphatase Isoenzymes, S No Yes
Sanford Laboratories - Sioux Falls/Rapid City Additional Information:

SANFORD LABORATORY INTERFACE BUILD INFORMATION

 Result Code     Result Code Description   
 17880  Alkaline Phosphatase
 17718  Alkaline Phosphatase Isoenzymes   
 28728  Liver %
 28729  Liver
 17723  Bone %
 17724  Bone 
 17725  Intestine %
 17726  Intestine