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Test ID NBLD0708 Porphyrins, Quantitative, Random, Urine

Useful For

Preferred test to begin assessment for congenital erythropoietic porphyria and porphyria cutanea tarda and during symptomatic periods for acute intermittent porphyria, hereditary coproporphyria, and variegate porphyria when specimen transport will not exceed 72 hours

Specimen Type

Urine


Ordering Guidance


This random urine test should be ordered when the specimen will reach Mayo Clinic Laboratories within 72 hours. If transportation will take longer than 72 hours, order PQNU / Porphyrins, Quantitative, 24 Hour, Urine and follow collection guidelines.



Shipping Instructions


Ship specimen in amber bottle to protect from light.



Necessary Information


Include a list of medications the patient is currently taking.



Specimen Required


Patient Preparation: Patient should not consume any alcohol for the 24 hours before specimen collection.

Supplies: Urine Container - Amber, 60 mL (T596)

Container/Tube: Amber, 60-mL urine container

Specimen Volume: 20 to 50 mL

Collection Instructions: Collect a random urine specimen.


Specimen Minimum Volume

15 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Urine Frozen 72 hours LIGHT PROTECTED

Reject Due To

  All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Day(s) Performed

Monday through Friday

Report Available

2 to 4 days

Method Name

High-Performance Liquid Chromatography (HPLC) with Fluorometric Detection/Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)

Reporting Name

Porphyrins, QN, Random, U

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Secondary ID

60597

CPT Code Information

84110-Porphobilinogen, quantitative

84120-Porphyrins, quantitation and fractionation

Reference Values

Uroporphyrins, Octacarboxyl:

≤30 nmol/L

 

Heptacarboxylporphyrins:

≤7 nmol/L

 

Hexacarboxylporphyrins:

≤2 nmol/L

 

Pentacarboxyporphyrins:

≤5 nmol/L

 

Copropprphyrin, Tetracboxyl:

≤110 nmol/L

 

Porphobilinogen:

≤1.3 mcmol/L

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

Testing Algorithm

The following algorithms are available:

-Porphyria (Acute) Testing Algorithm

 

-Porphyria (Cutaneous) Testing Algorithm 

 
Sanford Laboratories - Sioux Falls/Rapid City Additional Information:

SANFORD LABORATORY INTERFACE BUILD INFORMATION

 Result Code     Result Code Description   
 28373  Uroporphyrin
 28374  Heptacarboxylporphyrins   
 28375  Hexacarboxylporphyrins   
 28376  Pentacarboxylporphyrins   
 28377  Coproporphyrin, Tetra
 28378  Porphobilinogen
 28379  Interpretation