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Test ID NBLD0045 Alpha-Fetoprotein, Amniotic Fluid

Useful For

Screening for open neural tube defects or other fetal abnormalities

 

Follow-up testing for patients with elevated serum alpha-fetoprotein results or in conjunction with cytogenetic testing

Specimen Type

Amniotic Fld


Necessary Information


The following information is required:

1. Estimated due date by ultrasound

2. Collection date

3. Gestational age must be between 13 and 24 weeks; 16 to 18 weeks preferred.

 

If not ordering electronically, provide information on Second Trimester Maternal Screening Alpha-Fetoprotein / Quad Screen Patient Information (T595) and send with specimen.



Specimen Required


Container/Tube: Amniotic fluid container

Specimen Volume: 0.75 mL

Collection Instructions: Do not centrifuge.


Reject Due To

All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Amniotic Fld Refrigerated (preferred) 7 days
  Ambient  7 days

Day(s) Performed

Monday through Friday

Report Available

2 to 19 days

Method Name

AFPA: Immunoenzymatic Assay
ACHE_: Polyacrylamide Electrophoresis

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

82106

82013 (if appropriate)

Reporting Name

Alpha Fetoprotein, AF

Reference Values

< 2.0 multiples of median (MoM)

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
ACHE_ Acetylcholinesterase, AF Yes No

Testing Algorithm

If alpha-fetoprotein is positive, then acetylcholinesterase will be performed at an additional charge.

Secondary ID

9950
Sanford Laboratories - Sioux Falls/Rapid City Additional Information:

SANFORD LABORATORY INTERFACE BUILD INFORMATION

Result Code  Result Code Description 
17986 Collection Date
17987 EDD by US Scan
17988 Last Menstrual Period (LMP) 
17989 EDD by LMP
17990 GA at Collection by Scan
17991 GA at Collection by Dates
17992 GA Used
17993 Alpha Fetoprotein, AF
17994 Results
17995 Interpretation 
17996 Additional Comments
17997 Follow up
17998 General Test Info