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Test ID BLOD1718 Desmoglein 1 (DSG1) and Desmoglein 3 (DSG3), IgG Antibodies, Serum


Specimen Required


Collection Container/Tube:

Preferred: Red top

Acceptable: Serum gel

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions: Centrifuge and aliquot serum into a plastic vial.


Secondary ID

606818

Useful For

Preferred screening test for patients suspected to have an autoimmune blistering disorder of the skin or mucous membranes (pemphigus)

 

Aiding in the diagnosis of pemphigus

Method Name

Enzyme-Linked Immunosorbent Assay (ELISA)

Reporting Name

Desmoglein 1 and 3, Serum

Specimen Type

Serum

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 14 days
  Frozen  30 days
  Ambient  14 days

Reject Due To

Gross hemolysis OK
Gross lipemia OK
Gross icterus OK

Reference Values

DESMOGLEIN 1:

<20 RU/mL (negative)

≥20 RU/mL (positive)

 

DESMOGLEIN 3:

<20 RU/mL (negative)

≥20 RU/mL (positive)

Day(s) Performed

Varies

Report Available

1 to 10 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test has been modified from the manufacturer's instructions. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

83516 x 2

Sanford Laboratories - Sioux Falls/Rapid City Additional Information:

SANFORD LABORATORIES INTERFACE BUILD INFORMATION

 Result Code     Result Code Description   
 27727  DSG 1
 27728  DSG 3