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Test ID BLOD1612 CD4 T-Cell Recent Thymic Emigrants, Blood

Useful For

Evaluating thymic reconstitution in patients following hematopoietic cell transplantation, chemotherapy, immunomodulatory therapy, and immunosuppression

 

Evaluating thymic recovery in patients who are HIV-positive and on highly active antiretroviral therapy

 

Evaluating thymic output in patients with DiGeorge syndrome or other cellular immunodeficiencies

 

Assessing the naive T-cell compartment in a variety of immunological contexts (autoimmunity, cancer, immunodeficiency, and transplantation)

 

Identification of thymic remnants post-thymectomy for malignant thymoma or as an indicator of relapse of disease (malignant thymoma) or other contexts of thymectomy

Specimen Type

Whole Blood EDTA


Shipping Instructions


Testing is performed Monday through Friday. Specimens not received by 4 p.m. (CST) on Friday may be canceled.

 

Samples arriving on the weekend and observed holidays may be canceled.

 

Collect and package specimen as close to shipping time as possible. Ship specimen overnight in an Ambient Shipping Box-Critical Specimens Only (T668) following the instructions in the box.

 

It is recommended that specimens arrive within 24 hours of collection.



Necessary Information


Ordering healthcare professional name and phone number are required.



Specimen Required


Supplies: Ambient Shipping Box-Critical Specimens Only (T668)

Container/Tube: Lavender top (EDTA)

Specimen Volume: 3 mL

Collection Instructions: Send whole blood specimen in original tube. Do not aliquot.


Reject Due To

Gross hemolysis Reject
Gross lipemia Reject

Specimen Minimum Volume

1.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Whole Blood EDTA Ambient 48 hours PURPLE OR PINK TOP/EDTA

Day(s) Performed

Monday through Friday

Report Available

3 to 4 days

Method Name

Flow Cytometry

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

86356

Reporting Name

CD4 RTE, Flow Cytometry

Reference Values

CD4 Absolute

Males

1 month-17 years: 153-1745 cells/mcL

18-70 years: 290-1,175 cells/mcL

Reference values have not been established for patients that are younger than 30 days of age.

Reference values have not been established for patients that are older than 70 years of age.

 

Females

1 month-17 years: 582-1630 cells/mcL

18-70 years: 457-1,766 cells/mcL

Reference values have not been established for patients that are younger than 30 days of age.

Reference values have not been established for patients that are older than 70 years of age.

 

CD4 RTE %

Males

1 month-17 years: 19.4-60.9%

18-25 years: 6.4-51.0%

26-55 years: 6.4-41.7%

≥56 years: 6.4-27.7%

Reference values have not been established for patients that are younger than 30 days of age.

Reference values have not been established for patients that are older than 70 years of age.

 

Females

1 month-17 years: 25.8-68.0%

18-25 years: 6.4-51.0%

26-55 years: 6.4-41.7%

≥56 years: 6.4-27.7%

Reference values have not been established for patients that are younger than 30 days of age.

Reference values have not been established for patients that are older than 70 years of age.

 

CD4 RTE Absolute

Males

1 month-17 years: 50.0-926.0 cells/mcL

18-70 years: 42.0-399.0 cells/mcL

Reference values have not been established for patients that are younger than 30 days of age.

Reference values have not been established for patients that are older than 70 years of age.

 

Females

1 month-17 years: 170.0-1007.0 cells/mcL

18-70 years: 42.0-832.0 cells/mcL

Reference values have not been established for patients that are younger than 30 days of age.

Reference values have not been established for patients that are older than 70 years of age.

Test Classification

This test was developed using an analyte specific reagent. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.

Secondary ID

89504
Sanford Laboratories - Sioux Falls/Rapid City Additional Information:

SANFORD LABORATORY INTERFACE BUILD INFORMATION

 Result Code    Result Code Description  
 25458  CD4 Absolute (Cells/UL)
 25459    CD4 RTE%  
 25460    CD4 RTE Absolute
 25461    Interpretation