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HelpTest ID BLOD1582 Copeptin proAVP, Plasma
Useful For
Investigating the differential diagnosis for patients with water balance disorders, including diabetes insipidus, in conjunction with osmolality and hydration status
May aid in the evaluation of cardiovascular disease in conjunction with other cardiac markers
Specimen Type
Plasma EDTASpecimen Required
Patient Preparation: For water-deprivation testing, for at least 8 hours, the patient should fast and thirst (no liquids, including water, are allowed).
Collection Container/Tube: Lavender top (EDTA)
Submission Container/Tube: Plastic screw-top vial
Specimen Volume: 0.5 mL
Collection Information: Centrifuge and aliquot plasma into a plastic vial. Do not submit in original tube.
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | OK |
| Gross icterus | OK |
Specimen Minimum Volume
0.3 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Plasma EDTA | Refrigerated (preferred) | 7 days | |
| Frozen | 30 days | ||
| Ambient | 7 days |
Day(s) Performed
Monday through Saturday
Report Available
Same day/1 to 3 daysMethod Name
Immunofluorescent Assay (IFA)
Performing Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
84588
Reporting Name
Copeptin proAVP, PReference Values
Non-water deprived, non-fasting adults*: <13.1 pmol/L
Water deprived, fasting adults**: <15.2 pmol/L
Non-water deprived, non-fasting pediatric patients***: <14.5 pmol/L
Note:
*Keller T, Tzikas S, Zeller T, et al. Copeptin improves early diagnosis of acute myocardial infarction. J Am Coll Cardiol. 2010;55(19):2096-2106. doi:10.1016/j.jacc.2010.01.029
**Internal Mayo Clinic study
***Du JM, Sang G, Jiang CM, He XJ, Han Y. Relationship between plasma copeptin levels and complications of community-acquired pneumonia in preschool children. Peptides. 2013;45:61-65. doi:10.1016/j.peptides.2013.04.015
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.Secondary ID
603599SANFORD LABORATORY INTERFACE BUILD INFORMATION
| Result Code | Result Code Description |
|---|---|
| 24751 | Copeptin, ProAVP, P |