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Test ID BLOD1369 Voriconazole, Serum

Important Note

Trough Level:  Collect prior to next dose given.

Useful For

Monitoring trough levels of voriconazole is suggested for:

-Individuals with reduced liver function

-Individuals with cytochrome P450 (CYP) 2C19 alterations associated with poor metabolic function

-Patients taking other medications that affect CYP2C19 activity

-Patients experiencing potential toxicity

 

Monitoring trough levels may be reasonable in patients who are not responding optimally or have drug interactions that may decrease voriconazole levels or to ensure adequate oral absorption

Specimen Type

Serum Red


Specimen Required


Collection Container/Tube: Red top (serum gel/SST not acceptable)

Submission Container/Tube: Plastic vial

Specimen Volume: 2 mL

Collection Instructions: Centrifuge and aliquot serum into plastic vial within 2 hours of collection.


Reject Due To

Gross hemolysis OK
Gross lipemia OK
Gross icterus OK
 

Specimen Minimum Volume

0.6 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Red Refrigerated (preferred) 28 days
  Ambient  28 days
  Frozen  28 days

Day(s) Performed

Monday through Sunday

Report Available

Same day/1 to 2 days

Method Name

Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

80285

Reporting Name

Voriconazole, S

Reference Values

1.0-5.5 mcg/mL

Trough level (ie, immediately before next dose) monitoring is recommended.

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

Secondary ID

88698
Sanford Laboratories - Sioux Falls/Rapid City Additional Information:

SANFORD LABORATORY INTERFACE BUILD INFORMATION

Result Code  Result Code Description 
17333 Voriconazole, S