Test ID BLOD1326 Arylsulfatase A, Leukocytes
Useful For
Preferred enzymatic test for detection of arylsulfatase A deficiency
This test is not suitable for carrier detection.
Specimen Type
Whole Blood ACDShipping Instructions
For optimal isolation of leukocytes, it is recommended the specimen arrive refrigerated within 6 days of collection to be stabilized. Collect specimen Monday through Thursday only and not the day before a holiday. Specimen should be collected and packaged as close to shipping time as possible.
Specimen Required
Container/Tube:
Preferred: Yellow top (ACD solution B)
Acceptable: Yellow top (ACD solution A)
Specimen Volume: 6 mL
Collection Instructions: Send specimen in original tube. Do not aliquot.
Reject Due To
Gross hemolysis | Reject |
Specimen Minimum Volume
5 mL
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Whole Blood ACD | Refrigerated (preferred) | 6 days | YELLOW TOP/ACD |
Ambient | 6 days | YELLOW TOP/ACD |
Day(s) Performed
Preanalytical processing: Monday through Saturday
Assay performed: Tuesday
Report Available
2 to 8 daysMethod Name
Colorimetric Enzyme Assay
Performing Laboratory
Mayo Clinic Laboratories in RochesterCPT Code Information
82657
Reporting Name
Arylsulfatase A, LeukocytesReference Values
≥62 nmol/h/mg
Note: Results from this assay may not reflect carrier status because of individual variation of arylsulfatase A enzyme levels. Low normal values may be due to the presence of pseudodeficiency or carrier alleles. Patients with these depressed levels may be phenotypically normal.
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.Forms
1. New York Clients-Informed consent is required. Document on the request form or electronic order that a copy is on file. The following documents are available:
-Informed Consent for Genetic Testing (T576)
-Informed Consent for Genetic Testing-Spanish (T826)
2. Biochemical Genetics Patient Information (T602)
3. If not ordering electronically, complete, print, and send a Biochemical Genetics Test Request (T798) with the specimen.
Special Instructions
Secondary ID
8779Testing Algorithm
See Lysosomal Storage Disorders Diagnostic Algorithm, Part 2
SANFORD LABORATORY INTERFACE BUILD INFORMATION
Result Code | Result Code Description |
---|---|
16187 | Arylsulfatase A, Leukocytes |
16188 | Interpretation |
16189 | Reason for Referral |
16190 | Reviewed By |