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Test ID BLOD0204 Pyridoxal 5-Phosphate, Plasma

Important Note

Note:  Fasting overnight (12-14 hours). Infants-collect prior to next feeding. Water can be taken as needed.  For 24 hours prior to specimen collection, patient must not take multivitamins or vitamin supplements.

Green top (Sodium or Lithium Heparin) Plasma, Protect from light and FROZEN

Collection Instructions:

1. Centrifuge at 4° C within 2 hours of collection.

2. Aliquot all plasma into amber vial and freeze immediately.

 

Effective 3/21/2025:  Due to assay issues affecting PLP, results will be delayed past the published turnaround time. Specimens will be stabilized upon arrival and processed in the order they are received. Specimens may take up to 10 days to result and the duration of the delay is expected to last up to 30 days or more. An update will be provided when standard testing resumes.

 

Useful For

Determining vitamin B6 status, including in persons who present with progressive nerve compression disorders, such as carpal tunnel and tarsal tunnel syndromes

 

Determining the overall success of a vitamin B6 supplementation program

 

Diagnosis and evaluation of hypophosphatasia

Specimen Type

Plasma Heparin


Shipping Instructions


Ship specimen in amber vial to protect from light.



Specimen Required


Patient Preparation:

1. Patient should fast overnight (12-14 hours); infants-should have specimen collected before next feeding. Water can be taken as needed.

2. For 24 hours before specimen collection, patient should not take multivitamins or vitamin supplements.

Supplies: Amber Frosted Tube, 5 mL (T915)

Collection Container/Tube:

Preferred: Green top (sodium or lithium heparin) or Plasma gel separator (PST)

Acceptable: None

Submission Container/Tube: Amber vial

Specimen Volume: 1 mL

Collection Instructions:

1. Within 2 hours of collection, centrifuge at 4° C.

2. Aliquot all plasma into amber vial and freeze immediately.


Reject Due To

Gross hemolysis OK
Gross lipemia OK
Gross icterus OK

Specimen Minimum Volume

0.75 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Plasma Heparin Frozen 29 days LIGHT PROTECTED

Day(s) Performed

Monday through Thursday, Saturday, Sunday

Report Available

2 to 7 days

Method Name

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

84207

Reporting Name

Pyridoxal 5-Phosphate (PLP), P

Reference Values

5-50 mcg/L

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

Forms

If not ordering electronically, complete, print, and send a General Request (T239) with the specimen.

Secondary ID

42359
Sanford Laboratories - Sioux Falls/Rapid City Additional Information:

SANFORD LABORATORY INTERFACE BUILD INFORMATION

Result Code  Result Code Description 
17801 Pyridoxal 5-Phosphate (PLP)