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Test ID BLOD0177 Glucagon, Plasma

Useful For

Diagnosis and follow-up of glucagonomas and other glucagon-producing tumors

 

Assessing diabetic patients with problematic hyper- or hypoglycemic episodes (extremely limited utility)

Specimen Type

Plasma EDTA


Specimen Required


Patient Preparation: Fasting (8 hours)

Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube: Lavender top (EDTA)

Submission Container/Tube: Plastic vial

Specimen Volume: 2 mL

Collection Instructions:

1. Pre-chill lavender top (EDTA) tube at 4° C before drawing the specimen.

2. Draw blood into the pre-chilled tube and process as follows:

 a. Chill filled tube in wet ice for 10 minutes.

 b. Centrifuge in a refrigerated centrifuge or in a pre-chilled centrifuge carrier.

 c. Immediately after centrifugation, aliquot plasma into a plastic vial and freeze.


Reject Due To

Gross hemolysis Reject
Gross lipemia OK
Gross icterus OK

Specimen Minimum Volume

0.45 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Plasma EDTA Frozen 90 days

Day(s) Performed

Tuesday, Thursday

Report Available

3 to 7 days

Method Name

Immunoassay

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

82943

Reporting Name

Glucagon, P

Reference Values

≤6 hours: 100-650 pg/mL

1-2 days: 70-450 pg/mL

2-4 days: 100-650 pg/mL

4-14 days: declining gradually to adult levels

>14 days: ≤80 pg/mL (range based on 95% confidence limits)

 

Glucagon levels are inversely related to blood glucose levels at all ages. This is particularly pronounced at birth and shortly thereafter, until regular feeding patterns are established. This explains the higher levels immediately after birth, which then first fall as the glucagon release mobilizes the infant's glucose stores, then rise again as stores are depleted, finally normalizing towards adult levels as regular feeding patterns are established.

 

For International System of Units (SI) for Reference Values, see www.mayocliniclabs.com/order-tests/si-unit-conversion.html.

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

Forms

If not ordering electronically, complete, print, and send an Oncology Test Request (T729) with the specimen.

Secondary ID

9358
Sanford Laboratories - Sioux Falls/Rapid City Additional Information:

SANFORD LABORATORY INTERFACE BUILD INFORMATION

Result Code  Result Code Description 
1698 Glucagon