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HelpTest ID BLOD0106 Thyrotropin Receptor Antibody, Serum
Useful For
Recommended first-line test for detection of thyrotropin receptor antibodies
The following situations:
-Differential diagnosis of etiology of thyrotoxicosis in patients with ambiguous clinical findings and/or contraindicated (eg, pregnant or breast-feeding) or nondiagnostic thyroid radioisotope scans
-Diagnosing clinically suspected Graves disease (GD) (eg, extrathyroidal manifestation of GD include endocrine exophthalmos, pretibial myxedema, thyroid acropachy) in patients with normal thyroid function tests
-Determining the risk of neonatal thyrotoxicosis in a fetus of a pregnant female with active or past active GD
-Differential diagnosis of gestational thyrotoxicosis versus first trimester manifestation or recurrence of GD
-Assessing the risk of GD relapse after antithyroid drug treatment
Specimen Type
SerumSpecimen Required
Patient Preparation:
1. For 12 hours before specimen collection do not take multivitamins or dietary supplements containing biotin (vitamin B7), which is commonly found in hair, skin, and nail supplements and multivitamins.
2. Patient should not be receiving heparin treatment.
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | OK |
| Gross icterus | Reject |
Specimen Minimum Volume
0.75 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerated (preferred) | 7 days |
| Frozen | 90 days |
Day(s) Performed
Monday through Saturday
Report Available
1 to 3 daysMethod Name
Electrochemiluminescence Immunoassay
Performing Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
83520
Reporting Name
Thyrotropin Receptor Ab, SReference Values
≤1.75 IU/L
Test Classification
This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.Forms
If not ordering electronically, complete, print, and send a General Request (T239) with the specimen.
Secondary ID
81797SANFORD LABORATORY INTERFACE BUILD INFORMATION
| Result Code | Result Code Description |
|---|---|
| 13100 | Thyrotropin Receptor Ab, S |