Sign in →

Test ID NBLD0548 Iron, Liver Tissue

Useful For

Diagnosis of hemochromatosis using liver tissue specimens

Specimen Type

Liver Tissue


Necessary Information


Patient's date of birth is required to calculate iron index.



Specimen Required


Supplies: Metal Free Specimen Vial (T173)

Container/Tube:

Preferred: Mayo metal-free specimen vial

Acceptable: Paraffin block, with no more than 1 or 2 cuts previously made

Specimen Volume: 2 mg

Collection Instructions: Two mg of liver tissue are required. This is typically a piece of tissue from a 22-gauge needle biopsy at least 2 cm long. If an 18-gauge needle is used, the tissue must be at least 1 cm in length.

Additional Information: Paraffin blocks will be returned 7 days after analysis is complete.


Reject Due To

All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Specimen Minimum Volume

Needle biopsy: See Specimen Required; 2 mm x 2 mm (punch): 0.3 mg by dry weight

Specimen Stability Information

Specimen Type Temperature Time Special Container
Liver Tissue Refrigerated (preferred)
  Ambient 
  Frozen 

Day(s) Performed

Monday, Thursday

Report Available

3 to 6 days

Method Name

Inductively Coupled Plasma Mass Spectrometry (ICP-MS)

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

83540

Reporting Name

Iron, Liver Ts

Reference Values

Iron

Males: 200-2,400 mcg/g dry weight

Females: 200-1,800 mcg/g dry weight

 

Iron Index

≥13 years: <1.0 mcmol/g/year

Reference values have not been established for patients that are younger than 13 years.

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

Testing Algorithm

For more information see Hereditary Hemochromatosis Algorithm.

Secondary ID

8350
Sanford Laboratories - Sioux Falls/Rapid City Additional Information:

SANFORD LABORATORY INTERFACE BUILD INFORMATION

Result Code  Result Code Description 
20642 Iron, Liver TS
20643 Hepatic Iron Index