Test ID NBLD0150 HMA & VMA Urine
Useful For
This test is used in the diagnosis and monitoring of treatment of neuroblastoma and pheochromocytoma.
AKA
Homovanillic Acid
Vanilylmandelic Acid
Specimen Type/Requirements
Urine, Random or 24 Hour submitted in sterile specimen container
Urine absorbed onto filter paper
If using filter paper to obtain collection, obtain filter paper urine collection kit from the laboratory. The kit includes one 10 x 10 cm absorbent filter paper, patient identification form and directions for specimen collection. Collect as follows:
- In young infants, collect from a thoroughly wet diaper not contaminated with stool. Remove top layer of diaper if disposable type. Place filter onto diaper and place diaper on flat hard surface. Place filter paper between two wet portions of diaper and press with fingertips until the filter becomes wet. Do this until the entire filter is damp (filter will look darker).
- Ultra absorbency diapers may present a problem in collecting enough urine and are not recommended for this collection. If ultra absorbency diapers are used, place several cotton balls between the diaper and baby's genitals. The urine in the cotton ball can the be squeezed onto the filter paper.
- In toilet trained children, collect 5 ml urine.
Place filter paper on top of plastic bag or a clean non-absorbent surface and let filter paper dry. Label filter paper with patient name and Date of Birth and Collection in pencil ( do not use ink). Place dried filter paper and identification form in a plastic leakproof bag.
Specimen Volume
Preferred Volume | 5.0 mL |
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Minimum Volume | 2.0 mL |
Stability/Transport
Room Temperature - Urine | not acceptable | |
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Refrigerated - Urine | acceptable | preferred for transport |
Frozen - Urine | acceptable | |
Room Temperature - Filter Paper | acceptable | preferred for transport |
Refrigerated - Filter Paper | not acceptable | |
Frozen - Filter Paper | not acceptable |
Performed Test Frequency
Monday through Friday
Report Available
2 days
Additional Information
Drugs such as L-dopa, dopamine, epinephrine and norepinephrine are metabolized HVA and VMA and will fictitiously elevate their levels in the urine. Therefore, the patient should not be on such drugs when collecting the urine.
Methodology
Capillary Gas Chromatography/Mass Spectrometry
Performing Lab
Fairview U of MN
CPT
83150
84585
Interface Build Information
Result Code | Result Code Description |
---|---|
2182 | Homovanillic Acid Urine |
4099 | VMA (Vanillylmandelic Acid) Urine |