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HelpTest ID BLOD1804 Enhanced Liver Fibrosis (ELF), Serum
Useful For
As a prognostic marker in conjunction with other laboratory findings and clinical assessments to assess the likelihood of progression to cirrhosis and liver-related clinical events in patients with advanced fibrosis (F3 or F4) due to metabolic dysfunction-associated steatohepatitis (MASH)
Specimen Type
Serum
Specimen Required
Patient Preparation: For 12 hours before specimen collection, patient should not take multivitamins or dietary supplements (eg, hair, skin, and nail supplements) containing biotin (vitamin B7).
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL Serum
Collection Instructions: Within 2 hours of collection, centrifuge and aliquot serum into a plastic vial. Specimens that have not been aliquoted will be rejected.
Reject Due To
| Gross hemolysis | Reject |
| Thawing | Cold OK; Warm reject |
| Gross lipemia | OK |
| Gross icterus | OK |
Specimen Minimum Volume
Serum: 0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerated (preferred) | 7 days |
| Ambient | 48 hours | |
| Frozen | 365 days |
Day(s) Performed
Monday through Friday
Report Available
Same day/1 to 3 days
Method Name
Direct Chemiluminescent Immunoassay
Performing Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
81517
Reporting Name
Enhanced Liver Fibrosis (ELF), Serum
Reference Values
| ELF score | Risk of disease progression |
|---|---|
| ≥9.20 | Diagnostic cut-off for clinically significant fibrosis (fibrosis stage 2 or greater) |
| ≥11.30 | Prognostic cut-off for higher risk of progression to liver-related clinical events |
Test Classification
This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.
Forms
If not ordering electronically, complete, print, and send Gastroenterology and Hepatology Test Request (T728) with the specimen.
Sanford Laboratory Interface Build Information
| Result Code | Result Code Description |
|---|---|
| 29703 | Elf Score |