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Test ID BLOD0680 Antiphospholipid Antibody Panel

AKA

Phospholipid, Lupus, Hexagonal, DRVV 

Specimen Type/Requirements

Gold top (Serum w/gel) tube - Serum 

Red top (Serum w/out gel) tube - Serum

Blue top (Sodium Citrate) tube - Plasma, Double Spun Platelet Poor (2 separate frozen aliquots)

 

Note: Serum or Sodium Citrate Plasma may be used for the Cardiolipin Antibodies and the Beta 2 Glycoprotein, but Sodium Citrate is the only acceptable specimen type for the Lupus Inhibitor Screen and the Dilute Russell Viper Venom Time.  If serum is sent for a portion of the test, the aliquots should still be frozen and should be labeled as serum.

 

See  Coagulation Testing and Platelet Poor Plasma Preparation

 

Test is affected by hemolysis and lipemia.

Specimen Volume

Serum or Sodium Citrate aliquot for Cardiolipin IgG and IgM and Beta-2 Glycoprotein IgG and IgM:

 Preferred Volume     3.5 mL    
 Minimum Volume     2.5 mL   

Sodium Citrate aliquot for Lupus Inhibitor Screen:

 Preferred Volume     1.5 mL   
 Minimum Volume     1.5 mL

Sodium Citrate aliquot for Dilute Russell Viper Venom Time:

 Preferred Volume     2.0 mL   
 Minimum Volume     1.0 mL  

 

Stability/Transport

 Room Temperature     Not Acceptable     
 Refrigerated     Not Acceptable     
 Frozen     Greater than 7 days     Preferred for transport   

 

Performed Test Frequency

Testing for Cardiolipins and Beta 2 Glycoprotein is performed Monday through Friday
Testing for Dilute Russel Viper Venon Time is performed on Tuesday and Friday.
Testing for the Lupus Inhibitor Screen is performed on Tuesday and Friday.

Report Available

1 - 3  days

Additional Information

Testing includes : Cardiolipin IgG Antibody, Cardiolipin IgM Antibody, Lupus Inhibitor Screen, Beta 2 Glycoprotein IgG and IgM Antibody, and Dilute Russel Viper Venom Time.

 

Confirmation testing for the DRVV will be performed at an additional charge if indicated.

 

Abnormal results can be obtained in patients on anticoagulant therapy, including the newer agents (e.g. rivaroxaban, apixaban, etc.). This can result in false interpretation of lupus inhibitor.

Methodology

Multiplex Flow Immunoassay

Stagos Instrument

Performing Lab

Sanford Laboratories Sioux Falls

CPT

86146(2), 86147(2), 85613, 85598