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HelpTest ID BLOD0344 Valproic Acid, Free and Total, Serum
Useful For
Monitoring both total and free valproic acid levels in therapy
Assessing compliance
Evaluating potential toxicity
Specimen Type
SerumSpecimen Required
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 2 mL
Collection Instructions:
1. Serum gel tubes should be centrifuged within 2 hours of collection.
2. Red-top tubes should be centrifuged, and the serum aliquoted into a plastic vial within 2 hours of collection.
Reject Due To
| Gross hemolysis | Reject |
Specimen Minimum Volume
1 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 14 days | |
| Frozen | 28 days | ||
| Ambient | 72 hours |
Day(s) Performed
Monday through Sunday
Report Available
Same day/1 dayMethod Name
VALPA: Immunoassay
VALPF: Ultrafiltration Followed by Immunoassay
Performing Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
VALPA-80164
VALPF-80165
Reporting Name
Valproic Acid, Free and Total, SReference Values
VALPROIC ACID, TOTAL
Therapeutic: 50 (trough)-125 (peak) mcg/mL
Critical value: ≥151 mcg/mL
VALPROIC ACID, FREE
Therapeutic: 5-25 mcg/mL
Critical value: >30 mcg/mL
Test Classification
This test has been modified from the manufacturer's instructions. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.Forms
If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.
Profile Information
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| VALPF | Valproic Acid, Free, S | Yes | Yes |
| VALPA | Valproic Acid, Tot, S | Yes | Yes |
Secondary ID
37067SANFORD LABORATORY INTERFACE BUILD INFORMATION
| Result Code | Result Code Description |
|---|---|
| 5717 | Valproic Acid Free |
| 5603 | Valproic Acid Total |